& Curcumin Inhibit Prostate Cancer Cell Growth|
Keith D. Bishop, Clinical Nutritionist, B.Sc. Pharmacy - 01/07/2015
EGCG combined with curcumin inhibits prostate cancer cell growth in a laboratory study.
EGCG (Epigallocatechin gallate) and curcumin are well known
natural anticancer agents. In laboratory studies researchers evaluated the combined effect of curcumin and EGCG on
PC3 prostate cancer cells, which are resistant to chemotherapy.
EGCG showed weak growth inhibition effect on the PC3 prostate cancer cells and stronger growth
inhibition effect on LNCaP and DU145 prostate cancer cell lines.
Co-treatment of curcumin improved the growth inhibition effect on EGCG on PCE
prostate cancer cells. The co-treatment of curcumin and EGCG arrested both S and G2/M phases of cell division and
growth of the PC3 cells.
Curcumin is not well absorbed. I recommend taking curcumin with BioPerine (black
pepper extract) to increases the absorption and blood levels of curcumin. Diindolylmethane also has research
supporting its use against prostate cancer. Click here to learn about DIMension 3
(curcumin, diindolylmethane, and BioPerine) by Xymogen.
I use Xymogen Green Tea 600 for therapeutic source of
EGCG. Click here to learn about Green Tea
There are different types of prostate cancer cell lines with
different types of aggressiveness and sensitivity to chemotherapy, radiation and alternative treatments. This
article mentioned 3 cells lines. There are others. At the time I wrote this article doctors are NOT testing
prostate cells obtained from biopsies or prostate removal for cell lines. Please ask your doctor what your prostate
cancer cell line is. They will probably not have that information, but it will serve to enlighten them about
prostate cancer cell lines. Perhaps in the future men with prostate cancer will be able to customize their
traditional and natural treatment to improve their outcomes.
About the Author:
Keith D. Bishop, Clinical Nutritionist, B.Sc. Pharmacy (retired pharmacist), helps his clients improve their health
by using natural products, functional tests, diet, lifestyle and self care. He writes special reports, consults and
gives seminars on natural product, diet and lifestyle effects on cancer. You may schedule an appointment for customized natural cancer or
alternative cancer recommendations by calling 405.919.1982.
Click here to learn more about Alternative Cancer
BMB Reports. 2014 Dec 2. Synergistic effect of curcumin on epigallocatechin gallate-induced anticancer
action in PC3 prostate cancer cells. Eom DW, Lee JH, et al.