EGCG and Triple Negative Breast Cancer
EGCG (Epigallocatechin-3-Gallate), the major active
component of green tea, has anti-cancer effect on breast cancer cells.
Researchers exposed triple negative breast cancer cells to EGCG. They found EGCG subdues the
growth, metastasis and spreading of triple negative breast cancer cells by decreasing blood vessel growth to
breast cancer cells and tumors. The anti-cancer effect was seen at 24, 48 and 72 hours after
The same researchers previously found EGCG caused
significant death of triple negative breast cancer cells at 48 and 72 hours after treatment in their laboratory.
EGCG upregulated 18 and down regulated 4 cancer growth genes including BAG3, XIAP, RIPKS. These genes may be
associated with resistance to cancer treatment.
High doses work better than low doses of EGCG in
treating triple negative breast cancer. High doses caused oxidative damage, similar to chemotherapy
At the time of publication, the amount of EGCG and
triple negative breast cancer research is limited due to 2 facts:
- Triple negative breast
cancer is not common, even though is may be a problem for you. Since it is not at common researchers
can not get as much money.
- EGCG is an inexpensive
natural product and financially cannot be developed for prescription drug use.
Newer breast cancer research is finding combining
curcumin with EGCG enhances the effectiveness of the natural treatments in preventing cancer stem cell
growth although the combination has not been tested in triple negative breast cancer. Click pr tap here to learn more about triple negative
breast cancer and curcumin treatment.
Taking EGCG with piperine (BioPerine) increases the
blood level of EGCG in the body. Xymogen CurcuPlex has
Click or tap here to learn about Xymogen GreenTea 600.
Click or tap here
to learn about Xymogen CurcuPlex CR.
Return from EGCG
and Triple Negative Breast Cancer to Triple Negative Breast Cancer Alternative Treatment Strategies.